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For someone with healthy B12 levels, the smarter move may be semaglutide alone, with B12 added only if testing shows a need

[1]Sung-Hee Oh, Prevalence and Socioeconomic Burden of Diabetes Mellitus in South Korean Adults, BMC Public Health, bmcpublichealth.biomedcentral.com Sugar intake trends deepen the challenge, with one-fifth of children exceeding recommended levels

Injections bypass that step, so more B12 becomes available to tissues

One study reported one rat out of 8 expressing human islet amyloid polypeptide (HIP) as a model for diabetes developed pancreatitis when treated with sitaglyptin for 12 weeks (70)