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GLP-1 is secreted by intestinal L cells in response to food intake and promotes satiety, reduces food consumption, and delays gastric emptying through actions on the hypothalamus ( The theoretical rationale of the present study is grounded in emerging evidence that GLP-1 signaling extends beyond metabolic regulation and may influence reward processing and addiction-related neural circuits ( Importantly, this trial enrolls patients with T2DM receiving routine glucose-lowering therapy, thereby reflecting real-world clinical practice
Schellekens et al
Ditzenberger GL, Lake JE, Kitch DW, Kantor A, Muthupillai R, Moser C, et al
This story was originally published by Men's Journal on Jan 5, 2026, where it first appeared in the Health & Fitness section
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