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SBIR Phases Most SBIRs start with an application for a Phase I often a proof of concept that is expected to take between 6 and 12 months, with funding for $100,000 to $400,000 (depending upon agency and project area.) Applications usually take the form of a 6 to 12-page technical proposal, a project plan, a commercialization plan, a single page budget, personnel biographies, letters of support, and other relevant information

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LC/MS analysis of eight vitamin E isoforms in HeLa cells supplemented with human LDL and HDL (50 g/mL each), shown as fold change relative to lipoprotein-depleted cells