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In contrast, in in vivo assay, xCT-KO pancreatic ductal adenocarcinoma (PDAC) cells injected subcutaneously managed to form a tumor, although with a short delay
45 (Suppl): S19S26
Following the SUSTAIN-6 findings, the Ozempic Summary of Product Characteristics (SmPC) and specialist ophthalmology guidance emphasise the importance of: Assessing retinopathy status before initiating semaglutide Ensuring patients are up-to-date with diabetic eye screening Considering the rate of anticipated glycaemic improvement More frequent monitoring in high-risk individuals The consensus among UK diabetes specialists is that semaglutide remains an important therapeutic option, but prescribers should exercise particular caution in patients with established retinopathy and poor baseline glycaemic control
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