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Standard glutathione is often broken down by enzymes in the gut before it can ever reach your bloodstream
140 This induces hepatocyte pyroptosis via the classical pathway, releasing IL-1 and IL-18, which recruit immune cells and activate NF-B signaling, amplifying pro-inflammatory mediator production and promoting progression from simple steatosis to MASH
FIGURE 10 10 Metal chelators Various chelating agents have been used to inhibit metal-dependent oxidative damage
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