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12 weeks liraglutide-treatment of patients at high risk for dementia was also shown to increase connectivity in the default mode network supporting the fact that GLP-1R agonists may reduce or hinder the progression of Alzheimers disease (Watson et al., 2019)
For comparison, we treated cells with tunicamycin (TUN, a widely-used ER stress inducer) which did not alter phospho-GCN2 (T899), but reduced the mobility of PERK, indicative of its increased phosphorylation (Fig
The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group (2016) Intensive diabetes treatment and cardiovascular outcomes in type 1 diabetes: the DCCT/EDIC study 30-year follow-up
