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The study reveals that BPC-157-induced GHR expression increases sensitivity to growth hormone signaling: adding growth hormone to BPC-157-treated fibroblasts dose- and time-dependently increased cell proliferation (MTT assay and PCNA) and activated the downstream Janus kinase 2 (JAK2) pathway
Front Cell Infect Microbiol 14:1416537
i.e., they do not aggregate irreversibly or secrete although they bind TXA2, but they respond normally to thrombin
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