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The hypoglycemia stimulates glucagon release from the pancreas and epinephrine release from the adrenal glands leading to increased fatty acid release from adipose tissue
Fang X, Wang H, Han D, Xie E, Yang X, Wei J, et al
But the TMLHE gene is required for carnitine synthesis, so a mutation in this gene can lead to carnitine deficiency
Monitoring strategies should be individualized based on patient risk factors and align with FDA prescribing information, which recommends monitoring heart rate at regular intervals for some GLP-1 receptor agonists
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