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Our findings revealed that after transfection with STAT3-targeting siRNA (siSTAT3), the stimulant effect of GHK-Cu on the healing of MCECs and the effect on the protein expression of ZO-1 and Occludin is canceled
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While our efforts to define the endogenous ligand for NHR-49 were unsuccessful, mutating the ligand-binding pocket might allow us to determine the role of ligand binding in the transcriptional activity of NHR-49
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