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[8] Studies suggest that the peptide may mediate the release of insulin through the indirect excitation of calcium channels found on the islet cells
The Reduction in the Mitochondrial Membrane Potential in Aging: The Role of the Mitochondrial Permeability Transition Pore
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[2] Your GP may: Refer you to psychological services if anxiety symptoms are significant, including NHS Talking Therapies for anxiety and depression Consider whether anxiety treatment should be optimised before or alongside GLP-1 therapy, following NICE guidance for anxiety disorders Coordinate care with diabetes specialists, dietitians, and mental health professionals Review the risk-benefit balance of continuing GLP-1 treatment if mental health concerns arise Screen for and manage eating disorders according to NICE guidance before initiating or continuing weight-loss treatments Remember that GLP-1 medications are not a treatment for anxiety, and any mental health benefits are likely secondary to metabolic improvements
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