Simultaneously, several meta-analyses and guideline panels highlight that many claimed indications are supported only by low- to moderate-quality evidence, with significant heterogeneity between trials and frequent failure of some strains or formulations to demonstrate superiority over placebo in rigorous, well-controlled studies (2, 3)
The extended shelf life comes from the pen formulation, per the Novo Nordisk prescribing information (2022)
Headaches affect a small percentage of users, usually during the first week or two of administration
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