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Injection Procedure: Allow the pen to reach room temperature if refrigerated (15 to 30 minutes) Attach a new pen needle for each injection Prime the pen by dialing to the flow check symbol and pressing the dose button until a drop appears at the needle tip Dial to the prescribed dose Clean the injection site with an alcohol swab Pinch the skin at the abdomen, thigh, or upper arm Insert the needle at a 90-degree angle and press the dose button fully Hold the button for 6 seconds before withdrawing Do not rub the injection site Liraglutide can be injected at any time of day, independent of meals, though many users find that evening dosing reduces nausea interference with daytime eating
Vilsboll, H
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A conformational change may occur upon binding, potentially activating intracellular signaling pathways primarily involving G-proteins
