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Lalwani ND, Hanselman JC, MacDougall DE, Sterling LR, Cramer CT
Interestingly, p38 exhibits context-dependent effects: under physiological conditions (e.g., exercise), p38 promotes mitochondrial biogenesis and fiber-type remodeling (Vainshtein and Sandri, 2020)
We upregulated the expression of GCLC, GSS, or SLC7A11 in VRK2-KD PC cells, and investigated the effects of these genes on cell viability, ROS and GSH levels when provided exogenous ROS ter-tbutyl hydroperoxide (TBHP)
Fluorescence emission was measured using a spectrometer
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