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CDC is direct about the limits of preservatives in multi-dose vials: "The preservative does not have an effect on viruses nor does it provide complete protection against bacterial contamination." Some organisms are considerably harder to control than others

However, activation of caspase-3 was not essential for the execution of apoptosis-like cell death of RBCs, resulting in the hypothesis that caspases were required for appropriate erythropoiesis [23]