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Results Increased severity of liver injury and mortality of mice with hepsin deficiency during the early period after acetaminophen exposure To investigate the potential physiological role of endogenous hepsin in the early response to APAP-induced liver injury, we analyzed hepsin expression in wild-type mouse liver lysates following APAP treatment using western blotting (Fig

Chronic low-grade inflammation develops with long-term heavy drinking through persistent gut disruption, liver stress, and ongoing immune activation and is linked to higher risks of infection, organ damage, and age-related disease

Healthcare providers should counsel patients on recognizing early signs of acute pancreatitis to ensure prompt evaluation and management