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Subcutaneous injection (abdomen, thigh, or upper arm) Once daily, typically at night Refrigerate between 28 C (3646 F)

E., & Davis, R

In addition to producing the antioxidant glutathione, ME-3 also produces a glutathione-containing antioxidant enzyme named glutathione peroxidase and glutathione reductase, which reactivates or recycles glutathione. As mentioned above, ME-3 is the only substance we know of to function as a complete glutathione system to synthesize, increase cellular uptake and recycle/regenerate glutathione

Superoxide is primarily a byproduct of normal cellular metabolism that is generated in the mitochondria and cytoplasm ( Figure 2B ) and is an initiating free radical that can result in the formation of other reactive species such as hydrogen peroxide (H 2 O 2 ), hydroxyl radical, and peroxynitrite (52)