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Based on the 2026 Clinical Obesity review of 480,825 adults, the most commonly deficient nutrients in GLP-1 users are vitamin D (13.6% deficient by 12 months), iron (2630% lower ferritin than comparators), calcium, and B12
Battini V, Van Manen RP, Gringeri M, et al
PlexusDx emphasizes that semaglutide may indirectly increase cardiovascular strain in certain scenariosrapid weight loss can temporarily elevate heart rate, and dehydration from gastrointestinal side effects may reduce blood volume
CPT II Type 1 "muscle" phenotype, which is the most frequent clinical presentation, is characterized by recurrent episodes of muscle pain, rhabdomyolysis (a potentially fatal disease that occurs suddenly and with great force destroying skeletal muscle) and myoglobinuria
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