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Under physiological or untreated pathological conditions, mitophagy functions beneficially by maintaining mitochondrial integrity, reducing ROS accumulation, suppressing oxidative stress, and consequently decreasing angiogenesis and lesion viability in EESCs

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Brown MA, Stevenson EJ, Howatson G

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However, PTSD participants testing positive for cannabis on scan day ( n = 10) had nominally higher MPO concentrations ( p = 0.167, 26% higher) compared to PTSD participants who tested negative ( n = 15)

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They showed withdrawal symptoms from alcohol (n = 47) and opiates (n = 60)

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