In response, the liver produces an antioxidant called glutathione, which the body uses to remove the toxin before it can build up and damage the liver

Abbreviations EOC: Epithelial ovarian cancer OCCC: Ovarian clear cell carcinoma OEC: Endometrioid carcinoma ARID1A: AT-rich interactive domain-containing protein 1A PIK3CA: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PTEN: Phosphatase and tensin homolog KRAS: KRAS proto-oncogene TP53: Tumor protein p53 EAOC: Endometriosis-associated ovarian cancer SIR: Standardized incidence ratio CI: Confidence interval ER: Estrogen receptor beta ER: Estrogen receptor alpha BDNF: Brain-derived neurotrophic factor TrkB: Tropomyosin receptor kinase B (NTRK2) IHC: Immunohistochemistry ERE: Estrogen response element RTK: Receptor tyrosine kinase PI3K: Phosphatidylinositol 3-kinase AKT: Protein kinase B EMT: Epithelialmesenchymal transition TME: Tumor microenvironment MAPK/ERK: Mitogen-activated protein kinase/extracellular signal-regulated kinase JAK/STAT: Janus kinase/signal transducer and activator of transcription OR: Odds ratio HR: Hazard ratio IC50: Half maximal inhibitory concentration p-AKT: Phosphorylated AKT p-ERK: Phosphorylated ERK mTOR: Mechanistic target of rapamycin FFPE: Formalin-fixed, paraffin-embedded References Pearce CL, Templeman C, Rossing MA, Lee A, Near AM, Webb PM, Nagle CM, Doherty JA, Cushing-Haugen KL, Wicklund KG

It increases glutathione levels in the body below optimal levels due to aging and environmental stressors
then, we laparatomized the rat for portal vein, inferior vena cava, and abdominal aorta pressure recording