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B12 deficiency causes megaloblastic anemia, a condition causing dysfunctional and abnormally shaped red blood cells
Beyond sequence, epigenetic evidence points to an NNMT-linked signature in human adipose tissue, indicating the pathway is dynamically active in human fat biology, not only in laboratory animals
Inositol is a naturally occurring compound involved in cellular signaling and metabolic function
NNMT regulates methylation of nicotinamide, influencing intracellular pools of NAD+, a central cofactor in metabolic pathways
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