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April 30, 2026
287 This theoretical perspective shifts the focus from static oncogenic drivers to the dynamic stability and plasticity of the signaling network as a whole, explaining why monotherapies often fail and providing a rationale for combinatorial strategies that target network vulnerabilities
Most patients find this balanced approach sustainable, since total restriction often leads to unsustainable binge-restriction cycles
Muscle cramps can endure from a few seconds to several minutes, often causing lasting tenderness and swelling for up to 72 h after an episode
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