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[45] Synthesis [edit] A slightly yellow liquid at room temperature, it can be prepared by converting m -toluic acid (3-methylbenzoic acid) to the corresponding acyl chloride using thionyl chloride (SOCl 2 ), and then allowing this acyl chloride to react with an excess of diethylamine: [46] [47] History [edit] DEET was developed in 1944 [48] by Samuel Gertler [48] of the United States Department of Agriculture for use by the United States Army, [49] following its experience of jungle warfare during World War II
[10] [12] These interactions are supported by pharmacokinetic studies, clinical observations, and drug interaction databases
doi: 10.3390/molecules21060710
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