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Semaglutide is the active ingredient in several FDA-approved medications
Hearts were treated 3-4 times at 37 C with fresh Ca 2 + -free HBSS solution containing 0.125% trypsin to isolate cardiac tissue
In the past, several trials were terminated prematurely because the required number of events was accrued earlier than the estimated duration
12+ months: Weight loss peaks around 65 weeks, then stabilizes
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