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For example, taking Adderall earlier in the day can improve sleep

Bell KE, Snijders T, Zulyniak M, Kumbhare D, Parise G, Chabowski A, Phillips SM

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Indeed, lead has been shown to cause gut microbiota dysbiosis and hepatic metabolic disorder in zebrafish (Xia et al., 2018a), and a 2020 study established that cadmium exposure altered the intestinal microbiota in freshwater crayfish ( Procambarus clarkia ) with regards to richness, diversity and composition, while also causing histological changes in the intestines (Zhang et al., 2020b)