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therefore, it is more plausible that an effective vascular improvement is reached in mildmoderate vasculogenic ED patients, specifically mediated by l-ARG supplementation, as demonstrated by the evidence of PSV values compatible with absence of ED in a subset of mildmoderate vasculogenic ED patients at study completion
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To study the permeability of nanoparticles in vitro BBB models, which conform to the 3R principles with the minimalization the number of animal experiments, are widely used either in static [34] or in dynamic conditions by employing lab-on-a-chip systems [35]
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