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This happens because GLPs improve satiety, insulin-sensitivity and can decrease food noise, in the brain

Acute Gallbladder Disease: Rapid weight loss and the pharmacological action of GLP-1 agonists can increase the risk of cholelithiasis (gallstones) and cholecystitis

Women using oral contraceptives should consider additional non-oral or barrier contraception for 4 weeks after initiation and for 4 weeks after each dose increase