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On April 1, 2026, the FDA approved Eli Lillys FOUNDAYO (orforglipron) , the second oral GLP-1 approved for obesity, and arguably the one with the more patient-friendly convenience profile
Paolicchi, A
Common side effects of semaglutide include nausea, diarrhea, and headaches, while tamoxifen can cause hot flashes, fatigue, and mood changes
They mostly showed up during the step-up weeks and then calmed down as the body got used to it: Feeling sick (nausea) Being sick (vomiting) Diarrhoea or constipation Less hunger Feeling tired Where an injection is involved, the spot can react too a bit of redness, mild swelling, bruising, itching, or a small firm lump if the same spot is used again and again
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