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Common side effects include: Nasopharyngitis and upper respiratory tract infections the most frequently reported adverse effects (mechanism not fully established) Headache and dizziness reported in some patients, particularly during the initial weeks of treatment Gastrointestinal symptoms such as nausea or constipation, though these are generally mild Less common but important safety considerations include: Hypoglycaemia : Although the risk is low when a gliptin is used alone or with metformin, it increases when combined with a sulfonylurea or insulin

Una meta-analisi ha evidenziato che il supplemento di L-carnitina potrebbe migliorare la funzione del cuore nelle persone con insufficienza cardiaca, ma la ricerca insufficiente a determinare una possibile efficacia nel ridurre il rischio o nel trattamento

In a study (New-Onset Nonarteritic Anterior Ischemic Optic Neuropathy and Initiators of Semaglutide in US Veterans With Type 2 Diabetes) published on February 12, 2026, participants who started taking semaglutide were about 2 times more likely to develop NAION than participants who took sodium-glucose cotransporter-2 inhibitors

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