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Studies show that NNMT inhibition influences metabolic pathways associated with healthspan and longevity
Finally, as an activator of the apoptotic cascade, oxidation of 4-hydroxyproline by 4-hydroxyproline oxidase to ROS can inhibit the growth of cancer cells and promote their death (Cooper et al
Studies have not found increased cancer incidence from these peptides themselves
This is supported by the observation that basal acidification and glycolytic reserve were at basal levels at 24 h, but the compensatory glycolysis was increased at this time point
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