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the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor
Infection risk: Though the benzyl alcohol preservative inhibits bacterial growth in the vial, any lapse in sterility (dirty needle, etc.) can introduce pathogens
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The practical difference: AOD-9604 has a more predictable pharmacokinetic profile based on its Phase IIb data
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