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The strongest evidence for meaningful, long-term weight loss and cardiometabolic benefit is at the labeled maintenance doses reached using a slow, individualized titration
Cautions include history of pancreatitis, gallbladder disease, and diabetic retinopathy (particularly with semaglutide)
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Sterile water for injection does NOT contain a preservative and should only be used for single-dose reconstitution, as it provides no protection against microbial contamination after the first needle puncture
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