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The sublingual mucosa is not designed for large molecule absorption
The evidence-based approach synthesizes data from multiple drug classes to provide practical clinical recommendations
Additionally, B-12 supports a healthy metabolism by aiding in the breakdown of fats and proteins
Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey
