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Scientists are cracking the code for extracting useful molecules from substances designed to harm

Kokura, S., Wolf, R.E., Yoshikawa, T., Granger, D.N

This review article examines the translational evolution of glucagon-like peptide-1 receptor agonists (GLP-1RAs), tracing their progression from the discovery of exendin-4 in Gila monster venom to long-acting peptide analogues and the first orally delivered peptide therapy, oral semaglutide

The 7.2 mg dose was approved to help patients achieve deeper weight reductionproducing nearly 20% total weight loss in the STEP UP clinical trialsputting its efficacy much closer to that of tirzepatide