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After a week, you can increase to twice daily if your skin tolerates it well
The STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program, which evaluated once-weekly semaglutide 2.4 mg for weight management, demonstrated significant weight loss (approximately 15% in STEP 1) that could indirectly affect hormone levels, though testosterone was not systematically reported in these publications
Many patients experience stress weight gain when cortisol levels remain elevated for extended periods
This section explains which people should avoid using semaglutide and SSRIs together
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