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10.1016/S0140-6736(19)32131-2 86 McCreightL
Researchers should note that PT-141 produces a transient, dose-dependent increase in blood pressure it must not be used by individuals with cardiovascular disease, uncontrolled hypertension, or high cardiovascular risk, and must not be self-administered or used outside a controlled laboratory environment
Only one study showed that TC cell lines treated with lobeglitazone in vitro showed a significant reduction of TGF-1-induced EMT-associated processes and EMT markers expression reducing also cell migration and invasion