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When a REMS requires special distribution controls, restricted access programs, or mandatory safety testing, it can create practical barriers to generic entry because generic companies need samples of the reference product for bioequivalence testing, and if those samples are only available through controlled distribution channels, the innovator controls access
Effect of L-carnitine on the physical fitness of thalassemic patients
This is not a controlled human dose-ranging trial
Heres an in-depth look at the standard procedure, dosage guidelines, frequency of injections, and aftercare recommendations
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