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In vitro and in vivo analyses highlight its primary metabolite, Ac-LKKTE, as exhibiting the most pronounced activity related to cellular repair, with other metabolites such as Ac-LKK and Ac-LK exhibiting longer persistence but reduced bioactivity

GLP-1 receptor agonists, such as semaglutide (sold under the brand name Ozempic or Wegovy) and tirzepatide (brand name Mounjaro or Zepbound), are medications originally developed for diabetes and now approved for chronic weight management at specific doses

Flanagan JL, Simmons PA, Vehige J, Willcox MD, Garrett Q (April 2010)

At Lilly, the goal is to bring transformative medicines to the field and the opportunity to work on potential game-changers is a unique one