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Amino acids V12 (putative oxyanion hole), F112 (active site architecture), N108 (flavonoid binding) and C13 (GSH stabilization) were fully randomized by site saturation mutagenesis (NNK codons), and the created Pt GSTF8 variants were tested for conversion of flavan-3,3,4-triol ( 4 ) to cyanidin ( 8 ), and for their GSH-transferase activity towards CDNB ( 5 ) as a control of catalytic competence

At the 5mg/ml concentration, 100 units is straightforward but uses the entire syringe capacity

Nat Rev Neurosci 20(2):94108

Turmerics active compound curcumin has shown potent anti-platelet activity in preliminary studies