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Future trials should examine both induction and maintenance therapy applications, biomarker responses, and endoscopic healing outcomes to establish clinical utility
Everything here comes from published preclinical research
Although there is a broad clinical spectrum of glutathione synthetase deficiency, manifestations usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs (eg, respiratory distress, sepsis, hyperbilirubinemia) (62
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