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The Wnt/-catenin pathway is vital for osteogenic differentiation and bone formation (Grigorie & Lerner 2018)
This study further developed a cell death-related signature (CDS) based on CASP1, CYBB, PLA2G4A, and CTSS, providing an effective diagnostic tool that tightly correlates with progressive renal function decline and local immune microenvironment remodeling (135)
Fusion Proteins: Utilizing fusion proteins such as albumin or Fc fragments to increase the molecular weight of the drug, reducing rapid renal filtration and coordinating with other mechanisms to extend in vivo circulation time
Benefits: - Anti aging
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