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Pathogenic variants in three different genes have been shown to be associated with type 1 RTA

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

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These may include pregnancy testing, complete blood count to assess for anemia, thyroid function tests (as thyroid disorders commonly affect menstrual cycles), and reproductive hormone panels measuring FSH, LH, estradiol, and prolactin levels