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Compounded versions of semaglutide marketed as injections have not undergone any testing nor been approved by the FDA and therefore make them unavailable for marketing as an approved drug

Companies like Noom and Hims have also launched programs to prescribe microdosed GLP-1s, claiming that these smaller doses can reduce metabolic risk, lower inflammatory markers, and even lower the risk of cognitive decline. Evidence of sustained patient use post-shortage: Prescription volume and utilization of compounded semaglutide and tirzepatide have continued to grow despite the end of medication shortages, suggesting that compounders may be leveraging additives or dosage adjustments to justify production

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