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Medication should not be the first course of action, and current evidence does not support its effectiveness as a sole form of treatment, nor do medical guidelines recommend such use
Culley, L., Hudson, N
Because of all this, we strongly recommend avoiding it entirely
In pancreatic KRAS-mutated cancer cells, which can proliferate using albumin as the extracellular source of leucine, loss of SLC38A9 or its transport function strongly inhibited mTORC1 activation by macropinocytosed albumin as evidenced by cell proliferation and tumor formation (Goberdhan et al., 2016
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