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Their effectiveness has driven rapid uptake, with recent estimates suggesting that approximately 1.4 million Canadians are currently using a GLP-1 agent
GLP-1 RA use was associated with an elevated risk for gallbladder or biliary diseases in trials for weight loss (13 trials
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This degree of glucose lowering often enables patients to achieve their individualised HbA1c targets as recommended by NICE (typically 48 mmol/mol for most adults with type 2 diabetes, or 53 mmol/mol for those at risk of hypoglycaemia)
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