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Int J STD AIDS

Discuss at your next appointment if: you have reached week 8 with zero noticeable appetite or weight changes at your current dose, side effects are manageable but annoying and not improving, you are considering adjusting your dose escalation timeline, you want to explore combination approaches, or you are experiencing insomnia , menstrual changes , feeling unusually cold , or hormonal changes that you suspect are related to the medication

12: Johansen PB, Hansen KT, Andersen JV, Johansen NL

In the primary analysis using the trial product estimand, which evaluated participants who adhered to treatment, bodyweight decreased progressively in all active treatment groups over the 26-week period, without clear evidence of reaching a plateau