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This pool included several add-on trials (metformin HCl alone and in combination with a dipeptidyl peptidase-4 [DPP4] inhibitor and metformin HCl, or insulin and metformin HCl, 2 initial combination with metformin HCl trials, and 2 trials of patients with CVD and type 2 diabetes mellitus who received their usual treatment [with metformin HCl as background therapy])

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Iran J Pharm Res 13:11491156 Khalil M, Raila J, Ali M, Islam KMS, Schenk R, Krause J-P, Schweigert FJ, Rawel H (2012) Stability and bioavailability of lutein ester supplements from Tagetes flower prepared under food processing conditions

I wouldnt want my patients to think, I can just take this medication, and I never have to work out