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Description

In the SURPASS clinical trial program, which enrolled over 6,000 participants with type 2 diabetes, the most common side effects included nausea (reported in 12% to 29% of patients), diarrhea (13% to 16%), vomiting (5% to 10%), constipation (6% to 7%), and abdominal discomfort

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Although NMs significantly enhanced metabolite yields, further investigation is needed to gain deeper insight into the mechanisms underlying their effects on gene expression

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