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When these drugs were being developed, researchers observed that rats and mice exposed to high doses of GLP-1 RAs developed an increased incidence of C-cell hyperplasia (an overgrowth of specific thyroid cells) and medullary thyroid tumours
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Metabolic dysfunction is at the root of many chronic diseasesincluding type 2 diabetes, fatty liver disease (NAFLD), cardiovascular disease, and even certain cancers
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