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162,163 In addition, contrary to predicted increases based on the Randle hypothesis, elevated free fatty acid levels were associated with reduced intracellular G6P levels in acute lipid-induced IR and type 2 diabetics
FGF21, a liver-secreted hormone, has been proposed as a potential mediator of GCG actions to regulate hepatic metabolism 24
In other words, lowering your set point weight will increase the likelihood youll be able to keep the weight off
Once you understand the connection, you can address it
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