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At first the bodies of vegetarians and vegans did not produce much TMAO even when they took supplements, but after a few weeks they did, Hazen's team reported in the Journal of Clinical Investigation." In Medical Express on December 10, 2018 it was reported, "The findings suggest that measuring and targeting TMAO levels - something doctors can do with a simple blood test - may be a promising new strategy for individualizing diets and helping to prevent heart disease

HbA1c, triglycerides, blood pressure, and HDL cholesterol improved during weekly treatment and were largely maintained after the switch to reduced-frequency dosing

We dont push frameworks for the sake of process